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ESR & Erythrocyte Sedimentation Rate & Anticoagulation & Standardized Testing

Categories Vacuum Blood Test Tube
Brand Name: Orsin
Model Number: Gel Clot ActivatoR
Certification: ISO 13485
Place of Origin: China
MOQ: 100/pcs
Price: Negotiation
Payment Terms: L/C, D/A, D/P, T/T, Western Union
Supply Ability: 20million/pcs/moth
Delivery Time: 1-4 weeks
Feature: Superior Serum Yield
Tube Size: Customized pipe size
Productivity: 12000pcs/hour
Anticoagulant Forms: Sodium or lithium salt
Closure Type: Rubber Stopper
Tube Stopper: Rubber
Lead Time: 1-4 weeks
Color: Transparent
Tube Cap: Plastic
Tube Label: Paper
Packaging Material: PET/Glass
Manufacturer: Shanghai Orsin Medical Technology Co.Ltd
Closure Material: Synthetic rubber stopper
Characteristic: Liquid Biopsy
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ESR & Erythrocyte Sedimentation Rate & Anticoagulation & Standardized Testing

Core Functions

  1. Anticoagulation

    • Key additive: 3.2%–3.8% Sodium Citrate.

    • Blood-to-anticoagulant ratio: 4:1 (e.g., fill to "2mL" mark = 1.6mL blood + 0.4mL anticoagulant).

    • Mechanism: Chelates calcium ions → blocks coagulation cascade → maintains blood liquidity.

  2. Standardized Testing

    • Specialized dimensions (Ø 2.5mm × 200mm) → Complies with Westergren method (ICSH standard).

Primary Applications

1. Monitoring Inflammatory Diseases

ConditionClinical Utility
InfectionsBacterial TB → ESR ↑↑ >100 mm/h
Autoimmune diseasesActive RA → ESR ↑ (combined with CRP)
MalignanciesMultiple myeloma → Persistent ESR ↑ (therapy monitor)

2. Procedure (ICSH Protocol)

  1. Fill blood to the calibration mark → 2. Invert mix 8 times → 3. Place vertically in Westergren rack → 4. Stand undisturbed at RT for 60 min → 5. Measure plasma interface drop (mm) = ESR value.

3. Result Interpretation

ESR (mm/h)Clinical Implication
<20 (M) / <30 (F)Normal
20–50Mild elevation (e.g., chronic inflammation)
>50Significant elevation (active infection/tumor)

Critical Notes

1. Error Control

  • Fill volume deviation:

    ±10% error → ESR deviation up to 30% (Must fill exactly to the mark!).

  • Time sensitivity:

    Test >4h post-collection → RBC morphology alters → Falsely ↓ESR.

2. Interfering Factors

FactorESR EffectSolution
Anemia (Hct<30%)Falsely ↑Corrected ESR = ESR × [0.73+Hct]
Refrigerated sampleFalsely ↓Equilibrate to RT for 30 min
Underfilled tubeClot formationDiscard and recollect
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