Sitfloxafn Cas 127254-12-0 C19H18ClF2N3O3 101987-86-4 143062-84-4 144282-37-1

English Name:Sitafloxacin

Chemical drugs, antimicrobial agents, anti-inflammatory drugs

Sitafloxacin (INN; also called DU-6859a) is a fluoroquinolone antibiotic that shows promise in the treatment of Buruli ulcer. The molecule was identified by Daiichi Sankyo Co., which brought ofloxacin and levofloxacin to the market. Sitafloxacin is currently marketed in Japan by Daiichi Sankyo under the tradename Gracevit.

Essential information

Chinese Name: Citafloxacin Alias: 7-[(7S) -7-amino-5-aza [2.4] heptane-5-yl]-8-chloro-6-fluoro-1-[(1R, 2S) -cis-2-fluorocyclopropyl]-1,4-dihydro-4-oxo-3-quinoline carboxylic acid

English Name: Sitafloxacin

English alias: DU-6859a; Gracevit < <; 7 - ((S) - ((S) - 7 - Amino - 5 - Azaspiro [2.4] heptan - 5 - yl) - 8 - chloro - 6 - Fluoro - 1 - ((1R, 2S) - 2 - fluorocyclopropyl) - 4 - oxo - 1, 4 - dihydroquinoline - 3 - carboxylic acid; 7 - [(4S) - 4 - 4 - Amino - 6 - azo [2.4] heptan - 6 - yl] - 6 - Fluoro - 1 - ((1R, 2S) - 2 - fluorocyclopropyl) - 2 - fluorocyclopropyl) - 4 - oxo - 1, 4 - oxo - 1, 4 - dihydroquinoline[(2S) -2-fluorocyclopropyl]-4-oxoquinoline-3-carboxylic ACI D; 7-[(7S) - 7-amino-5-azaspiro [2.4] heptan-5-yl]-8-chloro-6-fluoro-1-[(2S) -2-fluorocyclopropyl]-4-oxoquinoline-3-carboxylic acid;

CAS: 127254-12-0

Molecular formula: C19H18ClF2N3O3

Molecular weight: 409.81400

Precise quality: 409.10000

PSA:88.56000

LogP:3.46790

Physicochemical properties

Density: 1.63 g/cm3

Boiling point: 629.2 C at 760 mmHg

Flash point: 334.3 x C

Refractive index: 1.698

Steam pressure: 1.06E-16mmHg at 25 degree C

     Hebei R&M Healthcare Company Limited was founded on April 29th, 2009 where locates in the industrial park of Zhao County in Shijiazhuang(Hebei Province). We specialized in production and trade stable series product of Ascorbic Acid. In addition, our company also mainly engaged in Ascorbic Acid related terminal product development, production and sale that provide high quality and stable product for the customers who come from different fields including Pharmaceutical, food, Aquaculture feed, Animal feed and cosmetic industry. In 2017, our company developed a series of new feed additive products and realized the custom process for Amino acid particles, three sucralose granules, spirulina granules and Roselle granules. All those new products make our products more diverse.

      With extensive work experience at important positions in large modern enterprises like CSPC Pharmaceutical Group Ltd., intermediate and above professional titles, bachelor or above degree, the top management is very experienced. The sales team is highly skilled. The production and technical staff are from institution with higher learning and professional granule production companies, so they are equipped with rich experience and fist-class techniques. In terms of management mode, we choose the operation mode of industrial giants like CSPC Pharmaceutical Group Ltd., as reference. What's more, we possess the advantages of small enterprises, such as flexible operation and rapid reaction.

     Our company began to strictly control the quality of the product from raw material purchase to quality management. There is always a belief in our staff mind and we stick to it from the startup that is "Leading technology, quality-oriented, management innovation and customer satisfaction”. Every production step is strictly in accordance with EU regulatory standards. In 2009, our company passed ISO9000, ISO22000, and in the same year we also passed KOSHER certificate. Thanks to the professional research team, every year there are new products are developed and the product structure is becoming more and more reasonable. Our company was awarded as " Small and medium sized enterprises of science and technology in Hebei province". Our company's product quality and service have been highly praised by customers and have established a brand image of business proficiency, management efficiency, service initiative, and excellent quality in the industry.

      With stable clients, smooth sales channels and sizzling sales, our products are exported to about 30 countries and regions such as the US, UK, Germany, other EU countries and Southeast Asia, winning high praise at home and abroad.

      Today, Runmin's employees adhere to the principle of “striving for truth and rigorous solidarity”, constantly stick to innovation, regard technology as the core, regard quality as their life, and regard users as God. We sincerely provide you with the most cost-effective products and meticulous after-sales services.