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Atropine Pharmaceutical Raw Materials For Cholinergic Receptor Antagonist Drugs

Categories Pharmaceutical Raw Materials
Brand Name: TINGYI
Model Number: CAS: 51-55-8
Certification: GMP,SGS,ISO9001:2008,KOSHER
Place of Origin: China
MOQ: 10g
Price: Negotiable
Payment Terms: Western Union, MoneyGram, Bank Transfer, Bitcoin
Supply Ability: 3000KG/Month
Delivery Time: Usually within 7 work days
Packaging Details: Stealth and discreet packaging
Product Name: Atropine
CAS: 51-55-8
MF: C17H23NO3
MW: 289.4
Purity: 95%
appearance: White Powder
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    Atropine Pharmaceutical Raw Materials For Cholinergic Receptor Antagonist Drugs

    High Quality and Purity Pharma Raw Materials Atropine CAS 51-55-8 for Cholinergic Receptor Antagonist Drugs


    Product Name: Atropine


    Product Details:



    Product Name


    Atropine

    Latin name

    Belladonna Extract

    Product source

    Atropa belladonna L.

    CAS NO.

    51-55-8

    Molecular formula

    C17H23NO3


    Molecular Weight (g/mol)


    289.4

    Melting point


    189-192 ° C (A)(lit. )

    EINECS


    200-104-8

    Appearance

    White Powder

    Analysis

    HPLC


    Purity (HPLC)


    95%

    Solubility


    Soluble

    Function

    for gastric alcer

    Storage

    Store in cool & dry place. Keep away from strong light and heat.

    Shelf Life

    2 years when properly stored


    Description:


    Atropine is a medication used to treat certain types of nerve agent and pesticide poisonings, some types of slow heart rate, and to decrease saliva production during surgery.It is typically given intravenously or by injection into a muscle.Eye drops are also available which are used to treat uveitis and amblyopia.The intravenous solution usually begins working within a minute and lasts half an hour to an hour.Large doses may be required to treat poisonings.


    Application:


    (1) relaxation smooth muscle: This product has a lot of relaxation of the role of visceral smooth muscle, excessive activity or in the spasm of the smooth muscle was a significant relaxation, and the impact of normal activities of the smooth muscle less.
    (2) inhibition of gland secretion: by blocking the M - cholinergic receptor inhibition of gland secretion. On the salivary glands and sweat glands of the most obvious inhibition. But also can lacrimal gland and respiratory gland secretion greatly reduced, but the impact of gastric acid secretion is smaller.
    (3) the role of the eye: atropine by blocking the pupil sphincter and ciliary muscle M-choline receptors and the performance of mydriasis, increased intraocular pressure and paralysis. These three effects have important clinical significance.
    (4) the role of cardiovascular: a larger dose (1 ~ 2mg) atropine can lift the vagus nerve inhibition of the heart, thus making heart rate. Large doses can expand the skin and visceral blood vessels, relieve small arterial spasm. The mechanism of dilation of blood vessels and the lifting of small vasospasm is unknown.
    (5) excitement of the central nervous system: high doses of irritability, more words and delirium and so on. Poisoning dose (more than 10mg) can produce hallucinations, orientation disorders, involuntary movement and convulsions and so on.


    Eyes:
    Topical atropine is used as a cycloplegic, to temporarily paralyze the accommodation reflex, and as a mydriatic, to dilate the pupils. Atropine degrades slowly, typically wearing off in 7 to 14 days, so it is generally used as a therapeutic mydriatic, whereas tropicamide (a shorter-acting cholinergic antagonist) or phenylephrine (an α-adrenergic agonist) is preferred as an aid to ophthalmic examination. In refractive and accommodative amblyopia, when occlusion is not appropriate sometimes atropine is given to induce blur in the good eye. Atropine eye drops have been shown to be effective in slowing the progression of myopia in children in several studies, but it is not available for this use, and side effects would limit its use.


    Heart:
    Injections of atropine are used in the treatment of bradycardia (a heart rate < 60 beats per minute). Atropine was previously included in international resuscitation guidelines for use in cardiac arrest associated with asystole and PEA, but was removed from these guidelines in 2010 due to a lack of evidence for its effectiveness.[13] For symptomatic bradycardia, the usual dosage is 0.5 to 1 mg IV push, may repeat every 3 to 5 minutes up to a total dose of 3 mg (maximum 0.04 mg/kg). Atropine is also useful in treating second-degree heart block Mobitz Type 1 (Wenckebach block), and also third-degree heart block with a high Purkinje or AV-nodal escape rhythm. It is usually not effective in second-degree heart block Mobitz type 2, and in third-degree heart block with a low Purkinje or ventricular escape rhythm. Atropine has also been used in an effort to prevent a low heart rate during intubation of children; however, evidence dose not support this use.



    Our Company Advantages:


    1, High quality with competitive price:

    1) Standard: U.S Standard
    2) All Purity≥99.8%
    3) We are manufacturer and can provide high quality products with factory price.


    2, Fast and safe delivery
    1) Parcel can be sent out within 8 hours after payment. Tracking number available
    2) Secure and discreet shipment. Various transportation methods for your choice.
    3) Customs pass rate ≥99.8%
    4)We provide re-ship policy.
    5) We have warehouse in Australia, Canada and England, we have large amounts of stock in the warehouse, can ship to you directly from our foreign warehouse!
    3, We have clients throughout the world.
    1) Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.
    2) Meeting customers's requirement is our responsibility.
    3) High quality, competitive price, fast delivery, first-class service gain the trust and praise from the customers.


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    Quality Atropine Pharmaceutical Raw Materials For Cholinergic Receptor Antagonist Drugs for sale
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