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Trilostane CAS 13647-35-3 Androgenic Steroids Used to Treat Heart Disease

Categories Anabolic Androgenic Steroids
Brand Name: Shuangbojie
Model Number: nutrition@chembj.com
Certification: Enterprise Standard
Place of Origin: China
MOQ: 10g
Price: Negotiation
Payment Terms: Western Union, MoneyGram, Bitocin, T/T
Supply Ability: 500kg/Month
Delivery Time: Within 24 hours
Packaging Details: Discreet Package
CAS: 13647-35-3
MF: C20H27NO3
MW: 329.43
EINECS: 237-133-0
Properties: Powder
Packing: Discreet Packing
WhatsAPP: +8618578209860
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    Trilostane CAS 13647-35-3 Androgenic Steroids Used to Treat Heart Disease


    Anabolic Androgenic Steroids Trilostane CAS 13647-35-3 Treat Heart Disease


    Product Name: Trilostane
    Synonyms: TRILOSTANE;(2-alpha,4-alpha,5-alpha,17-beta)-4,5-epoxy-17-hydroxy-3-oxoandrostane-2-car;17-beta)-ph;4-alpha,5-epoxy-17-beta-hydroxy-3-oxo-5-alpha-androstane-2-alpha-carbonitril;4-alpha,5-epoxy-3,17-dihydroxy-5-alpha-androst-2-ene-2-carbonitrile;4-alpha-5-epoxy-17-beta-hydroxy-3-oxo-5-alpha-androstane-2-alpha-carbonitril;androstane-2-carbonitrile,4,5-epoxy-17-hydroxy-3-oxo-,(2-alpha,4-alpha,5-al;modrenal
    CAS: 13647-35-3
    MF: C20H27NO3
    MW: 329.43
    EINECS: 237-133-0


    Trilostane Usage


    Uses in dogs Trilostane was withdrawn from the United States market in April 1994. However, it was approved in 2008 for the treatment of Cushing's disease (hyperandrenocorticism) in dogs.
    It is also the first drug approved to treat both pituitary- and adrenal-dependent Cushing's in dogs.
    1. has kidney or liver disease.
    2. takes certain medications used to treat heart disease.
    3. pregnant.
    4. taking other medicines, including those available to buy without a prescription, herbal or complementary medicines.
    5. had an allergic reaction to this or any other medicine.


    The treatment of advanced breast cancer Breast cancer is the most common type of tumor in women. Currently, for postmenopausal patients with hormone receptor-positive or unknown, clinical treatments unanimously recommend to be the preferred antiestrogen therapy, and the role of this therapy in delaying disease progression and improving survival time also has been affirmed and confirmed in numerous studies of breast cancer.


    Trilostane (trade name Modrenal) developed by the biotechnology company has already been on the market. It can be used for the treatment of postmenopausal women that hormone-selective cancer has spread outside the breast. The pharmaceutical uses two ways to slow down the disease progression. For hormone-sensitive breast cancer, estrogen promotes the growth of cancer cells by acting to the two receptors. Estrogen receptor α is cancer accelerator, and estrogen receptor β is the brake. Modrenal strengthens estrogen adsorption to the estrogen receptor β, and weakens the adsorption to estrogen receptor α. Meanwhile it also acts on another loci AP1in cell DNA to reduce cell proliferation.


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