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Safe 330784-47-9 Sex Steroid Hormones High Purity Avanafil 1-Dehydropiandrosterone

Safe 330784-47-9 Sex Steroid Hormones High Purity Avanafil 1-Dehydropiandrosterone

Country/Region china
Company Tai'an Jia Ye Biological Technology Co.,Ltd
Categories Sex Steroid Hormones
Update 2016-12-23 12:00:31
Brand Name: Nanjian
Model Number: WH20160112
Certification: ISO9001
Place of Origin: China
Minimum Order Quantity: Negotiation
Price: negotiable
Payment Terms: L/C, T/T, Western Union, MoneyGram
Supply Ability: 1000kg per month
Delivery Time: 2-3working days
Packaging Details: Disguised Or Discreet
Alias: 1-Dehydropiandrosterone
Appearence: White Crystalline Powder
Molecular Formula: C23H26ClN7O3
Molecular Weight: 483.9506
Purity: 99%
Company Info
Tai'an Jia Ye Biological Technology Co.,Ltd
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Safe 330784-47-9 Sex Steroid Hormones High Purity Avanafil 1-Dehydropiandrosterone


 

Safe 330784-47-9 Sex Steroid Hormones High Purity Avanafil 1-Dehydropiandrosterone

 

 

Detailed Product Description
 
Other nameAvanafil
 CAS330784-47-9
Molecular FormulaC23h26cln7o3
 Molecular Weight483.9506
 Assay99% Min.
CharacterWhite to Cyrstalline Solid

 

Avanafil Description:

Avanafil is a PDE5 inhibitor approved for erectile dysfunction by FDA on April 27, 2012 and by EMA on June 21, 2013. Avanafil acts by inhibiting a specific phosphodiesterase type 5 enzyme which is found in various body tissues, but primarily in the corpus cavernosum penis, as well as the retina. Other similar drugs are , tadalafil and vardenafil. The advantage of avanafil is that it has very fast onset of action compared with other PDE5 inhibitors. It is absorbed quickly, reaching a maximum concentration in about 30-45 minutes. About two-thirds of the participants were able to engage in sexual activity within 15 minutes.

In addition to the active ingredient, avanafil, each tablet contains the following inactive ingredients: mannitol, fumaric acid, hydroxypropylcellulose, low substituted hydroxypropylcellulose, calcium carbonate, magnesium stearate, and ferric oxide yellow.

 

Usage:


It is a development of the phosphodiesterase type 5 inhibitors, for the treatment of male sexual dysfunction, at present in the America, EU and Japan have completed phase II clinical trials, phase III clinical trials will start. The product is composed of Japanese Tanabe Pharma Company and VIVUS company development. In addition to oral dosage forms, VIVUS company is also developing Avanafil urethral administration, for not responding to oral dosage forms of patients.

Avanafil is a potent, highly selective phosphodiesterase 5 inhibitor, in vitro experiments showed that the selectivity of phosphodiesterase 5 stronger than . The compound dear compliance weak against other phosphodiesterase, and effect of adenosine receptor decreased, suggesting that the cardiovascular effects of avanafil should be weaker than .

Pre clinical study showed that avanafil and organic nitrate drugs taken in combination to reduce its on blood pressure was significantly weaker than and nitrate drugs with clothes. Moreover, avanafil inhibition of phosphodiesterase 6 is very weak, the relevant visual disturbance suppression may the enzyme phosphodiesterase 5 inhibitor induced and other.

 

 

COA:

 



Test Items

Specification

Test Results

Description

White or off-white crystalline powder

Off-white crystalline powder

Specific rotation

-56°~-60°

-58.2°

Identification

IR

Matches with working standard

Complies

HPLC

Solubility

Freely soluble in chloroform and in alcohol; Very slightly soluble in water

Conform

Heavy metals

≤10ppm

<10ppm

Water

≤0.3%

0.22%

Residue on ignition

≤0.1%

0.05%

Relative material

Maximum impurities≤0.5%

0.36%

Total impurities≤1.0%

0.52%

Assay

98.5~101.0%

99.68%

Conclusion

The specification conform with Enterprise standard



 

 

 

Packaging & Delivery

1). We promise to provide high purity of raw steroid powders & semi-finished liquid;

2). We have professional packing team always find new ways to make the disguised package for custom pass guaranteed;

3). We have Long term cooperation Express courier companies to delivery your goods safe and speedy door to door;

4). We always thinking more for customers, 24/7 good after-sale service to solve the problems at any time;

5). Resend policy once the parcel delivery failed by accident.

 

 

Product Tags:

raw hormone powders

  

anabolic steroid hormones

  
Safe 330784-47-9 Sex Steroid Hormones High Purity Avanafil 1-Dehydropiandrosterone

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